Conan O'Brien's Wife Liza Powell O'Brien: Her Inspiring Story

A Star-Studded Podcast Featuring Incredible Voices

Let me tell you about a truly remarkable podcast that has captured the hearts of listeners everywhere. Narrated and written by the incredibly talented Liza Powell O'Brien, this podcast features the voices of some of Hollywood's finest talents, including Megan Mullally, Nick Offerman, Jameela Jamil, Rita Wilson, Timothy Olyphant, Lisa Kudrow, and many more. These actors bring Liza’s captivating stories to life in ways that will leave you spellbound.

A Life Shaped by Creativity

Born Elizabeth Ann Powell on November 12, 1970, in Bainbridge Island, Washington, Liza grew up surrounded by creativity. Her father, Jake Powell, was the guitarist for a Dixieland band, and he has been playing at a New Orleans Creole restaurant every Monday for over two decades. Growing up in such a musical household undoubtedly fueled Liza's passion for storytelling and the arts.

Conan and Liza: A Love Story for the Ages

Conan O’Brien’s love story with his wife, Liza Powell O’Brien, is one for the ages. Their journey began in 1999, when they first met on the set of "Late Night with Conan O’Brien." It wasn’t long before their connection blossomed into something special. In 2002, they tied the knot in a private ceremony at St. James Cathedral in Seattle, Washington. Their family grew with the arrival of their daughter Neve in 2003 and their son Beckett in 2005. This close-knit family unit has been a source of strength and joy for both Conan and Liza.

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Her Passion for Writing and Storytelling

Liza Powell O’Brien holds an MFA in Fiction Writing from Columbia University's School of the Arts. Her work has graced prestigious stages across the country, including the Geffen Playhouse, Echo Theater Company, The Blank Theatre, and many others. Whether it's through her plays, her podcast "Significant Others," or her writing, Liza has made a name for herself as a powerful voice in the world of storytelling.

Conan’s Oscars Hosting and Liza’s Support

In 2025, Conan O’Brien will take the stage as the host of the Academy Awards. As always, Liza Powell O’Brien will be right there by his side, cheering him on with all the love and support that has kept their relationship strong for over two decades. Their bond is a testament to the power of partnership and mutual respect.

Behind the Scenes: Liza’s Podcasting Adventures

Liza is the driving force behind the popular podcast "Significant Others," where she delves into the intimate relationships that have shaped the lives of famous figures. On an episode of her husband’s podcast, "Conan O’Brien Needs a Friend," Liza shared some fascinating insights into her nonfiction work. This podcast is not just a side project—it’s a labor of love that showcases her deep understanding of human connections.

From Bainbridge Island to Hollywood

Liza grew up on Bainbridge Island, Washington, a picturesque place that seems worlds away from the glitz and glamour of Hollywood. Yet, her roots in this serene environment have grounded her throughout her career. Liza and Conan first met during the filming of an episode of "Late Night with Conan O’Brien" in 2000. Their relationship developed over time, leading to their marriage in 2002. They celebrated their union with a small, intimate ceremony surrounded by family and friends.

A Career Beyond Being Conan’s Wife

While many might know Liza as Conan O’Brien's wife, she is so much more than that. A playwright, podcast host, and writer, Liza has carved out a successful career for herself. Her debut novel, "Leaving the City Beautiful," was published in 1998, and in 2018, she received the prestigious Wallace Stevens Award for Poetry. Her work continues to inspire and resonate with audiences around the world.

Celebrating Liza: A Woman of Many Talents

Liza Powell O’Brien might be best known as Conan O’Brien's wife, but there’s so much more to her story. She’s a devoted mother to their two children and a dedicated professional who has built a thriving career in scriptwriting. After leaving her job as an advertising executive, Liza pursued her passion for storytelling, proving that it’s never too late to chase your dreams. Her journey is a testament to the power of hard work, determination, and following your heart.